Technologies

Technology Title
CRISPR Gene Editing Technology1
Category
Bioscience Medical
Short Description
A revolutionary gene editing technology that enables precise and efficient editing of DNA sequences.
Long Description

CRISPR-Cas9 is a groundbreaking gene editing tool that has transformed the field of genetics and genomics. It allows for precise and efficient editing of DNA sequences by leveraging a naturally occurring defense mechanism found in bacteria. The system consists of two primary components: the Cas9 enzyme, which acts as molecular scissors, and a guide RNA (gRNA), which directs Cas9 to the specific location in the genome where the edit is desired. The process begins with the design of a gRNA that is complementary to the target DNA sequence. The gRNA and Cas9 enzyme are then introduced into the cell, where they form a complex that searches for the target sequence. Once the target is found, the Cas9 enzyme cleaves the DNA at that site, creating a double-stranded break. The cell's natural repair machinery is then activated, and researchers can supply a template for repair that includes the desired edit. This template is incorporated into the genome, allowing for precise changes to be made to the DNA sequence. CRISPR-Cas9 has numerous applications, including the treatment of genetic diseases, the development of novel therapies, and the improvement of crop yields. Its precision, efficiency, and versatility have made it a widely adopted tool in research and industry, revolutionizing the field of gene editing and opening up new possibilities for basic research, biotechnology, and medicine.

Potential Applications
Treating genetic diseases, Cancer therapy, Gene therapy for inherited disorders, Crop improvement and genetic modification in agriculture, Development of novel biotechnological products, Gene editing for infectious disease prevention, Synthetic biology and bioengineering applications, Treatment of genetic disorders in humans, Gene editing for regenerative medicine, Forensic analysis and DNA identification
Image
Project Image
Organizations
World Health Organization (WHO)
Tags
Bioscience
Patent Information Link
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